Genetic Toxicology Laboratory

About | English

In the Drosophila Genetics Laboratory, toxicological studies are conducted with 14 different Drosophila mutants. Toxicity tests of various components, including nanoparticles, pesticides, sweeteners, and preservatives, are investigated here. Parameters such as mutation, recombination, neuromotor disorders, behavioral and developmental disorders are tested in Drosophila larvae and adults.

In the Genetic Toxicology Laboratory, DNA break analysis is performed on Drosophila, Allium cepa, and various cell lines. Studies on protein and enzyme activities and gene expression analysis in Drosophila are also conducted.

Projects:

• Investigation of the Neuroprotective Effect of CeO2 NP-Syringic Acid Composite in Drosophila melanogaster – Tübitak 1001 – 2024-2026

• Evaluation of Toxic Effects of Quaternary Ammonium Silane Compounds with Different Chain Lengths and Structures in Drosophila melanogaster and Allium cepa – Tübitak 1001 – 2021-2024

• Evaluation of Genotoxic Potential of Some Nano Silver Halides Using Different Test Systems – Tübitak 1001 – 2017-2019

• Investigation of Genotoxic Potentials of Some Fungicides Using Drosophila Smart and Comet Methods – Tübitak 1001 – 2016-2017

• Investigation of Antigenotoxic Effects of Resveratrol, Melatonin, and Ascorbic Acid Against Genotoxicity Induced by Silver and Cobalt Nanoparticles in Somatic Cells of Drosophila melanogaster – Tübitak 1002 – 2013-2015

• Investigation of the Genotoxic Potential of Silicon Dioxide Nanoparticles of Different Nano Sizes in vitro Using Drosophila Smart and Comet Methods – Tübitak 1002 – 2012-2013

• Investigation of the Mutagenic and Recombinogenic Effects of Aluminum Oxide, Titanium Dioxide, and Zirconium Oxide Nanoparticles Using the Drosophila Smart Method – Tübitak 1002 – 2011-2012

• Investigation of the Insecticidal and Genotoxic Effects of Synthetic Pyrethroid and Piperonyl Butoxide (PBO) Mixtures at Different Ratios on Drosophila melanogaster – Tübitak 1001 – 2007-2009

• Investigation of the Antimutagenic Effect of Chlorophyll a, Chlorophyll b, and Chlorophyllin Against UV – Tübitak 1002 – 2005-2006

• Investigation of the Mutagenic and Recombinogenic Effects of Certain Antidepressant Drugs in Drosophila melanogaster – Tübitak 1002 – 2003-2004

• Investigation of in vivo Adaptive Response Against UV in Drosophila melanogaster – Tübitak 1001 – 2002-2006

• Principal Investigator (PI): Prof. Dr. Bülent Kaya
  Address: Akdeniz University, Faculty of Science, Ground Floor, No: 20
  Phone: +90 242 310 23 50